Fertility Supplements: What Supplements Should You Take if You Are Trying To Get Pregnant?

Dr. Natalie Crawford, board certified fertility doctor, talks about fertility supplements. What supplements should you be taking if you are TTC? What do you need if you are trying to get pregnant? What supplements help improve your fertility? What supplements help diminished ovarian reserve and egg quality? What supplements help endometriosis or PCOS?

One of the top questions asked is “Are there any supplements I can take to improve my fertility?” – in this video the following are reviewed:
Prenantal Vitamins
Folic Acid
Methylated Folate
Vitamin D
Vitamin B12
CoQ10 (ubiquinol)
Vitamin C
Vitamin E
DHEA
Myoinositol

*all information is for medical education only and is not medical advice. Please ask your doctor about medical advice and recommendations for your situation.

References discussed:
Gaskins AJ, Chavarro JE. Diet and fertility: a review. Am J Obstet Gynecol. 2018 Apr;218(4):379-389. doi: 10.1016/j.ajog.2017.08.010. Epub 2017 Aug 24.

Toivonen KI, Lacroix E, Flynn M, Ronksley PE, Oinonen KA, Metcalfe A, Campbell TS. Folic acid supplementation during the preconception period: A systematic review and meta-analysis. Prev Med. 2018 Sep;114:1-17. doi: 10.1016/j.ypmed.2018.05.023. Epub 2018 May 23.

Servy EJ, Jacquesson-Fournols L, Cohen M, Menezo YJR. MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs folic acid: a key to pregnancy outcome: a case series. J Assist Reprod Genet. 2018 Aug;35(8):1431-1435. doi: 10.1007/s10815-018-1225-2. Epub 2018 Jun 7. PMID: 29882091;

Rudick BJ, Ingles SA, Chung K, Stanczyk FZ, Paulson RJ, Bendikson KA. Influence of vitamin D levels on in vitro fertilization outcomes in donor-recipient cycles. Fertil Steril. 2014 Feb;101(2):447-52. doi: 10.1016/j.fertnstert.2013.10.008. Epub 2013 Nov 5.

Ansariniya H, Hadinedoushan H, Javaheri A, Zare F. Vitamin C and E supplementation effects on secretory and molecular aspects of vascular endothelial growth factor derived from peritoneal fluids of patients with endometriosis. J Obstet Gynaecol. 2019 Nov;39(8):1137-1142.

Florou P, Anagnostis P, Theocharis P, Chourdakis M, Goulis DG. Does coenzyme Q10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta-analysis of randomized-controlled trials. J Assist Reprod Genet. 2020 Oct;37(10):2377-2387. doi: 10.1007/s10815-020-01906-3. Epub 2020 Aug 7.

Zhang Y, Zhang C, Shu J, Guo J, Chang HM, Leung PCK, Sheng JZ, Huang H. Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis. Hum Reprod Update. 2020 Feb 28;26(2):247-263.

Unfer V, Nestler JE, Kamenov ZA, Prapas N, Facchinetti F. Effects of Inositol(s) in Women with PCOS: A Systematic Review of Randomized Controlled Trials. Int J Endocrinol. 2016;2016:1849162. doi: 10.1155/2016/1849162. Epub 2016 Oct 23.

https://www.cdc.gov/ncbddd/birthdefects/surveillancemanual/chapters/chapter-4/chapter4-2.html

#fertility #supplements #nataliecrawfordmd
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Dr. Natalie Crawford, MD is a double board certified OBGYN and REI, and co-founder of Fora Fertility, a boutique fertility practice in Austin, Texas.

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Sharing fertility facts to educate women about trying to conceive, getting pregnant, ovulation, fertility treatments, IUI, IVF, becoming a doctor, life as a woman in medicine, and more.